G Protein Signaling Mediates Developmental Processes and Pathogenesis of Alternaria alternata

A review of Alternaria alternata sensitivity.

Sensitivity to fungi is a major risk factor for the development of asthma. However, the prevalence of fungal sensitivity in asthma is not completely understood. Nonetheless upward of 80% of asthmatic patients may be sensitized to one or more fungi. Fungal exposure occurs primarily from outdoors sources, but can occur in the indoor environment as well. Assessment of fungal exposure requires a mu...

Csn5 Is Required for the Conidiogenesis and Pathogenesis of the Alternaria alternata Tangerine Pathotype

The COP9 signalosome (CSN) is a highly conserved protein complex involved in the ubiquitin-proteasome system. Its metalloisopeptidase activity resides in subunit 5 (CSN5). Functions of csn5 in phytopathogenic fungi are poorly understood. Here, we knocked out the csn5 ortholog (Aacsn5) in the tangerine pathotype of Alternaria alternata. The ΔAacsn5 mutant showed a moderately reduced growth rate ...

Establishment of CRISPR/Cas9 in Alternaria alternata.

The filamentous fungus Alternaria alternata is a potent producer of many secondary metabolites, some of which like alternariol or alternariol-methyl ether are toxic and/or cancerogenic. Many Alternaria species do not only cause post-harvest losses of food and feed, but are aggressive plant pathogens. Despite the great economic importance and the large number of research groups working with the ...

Comparative Genomics of Pathogens Causing Brown Spot Disease of Tobacco: Alternaria longipes and Alternaria alternata

The genus Alternaria is a group of infectious/contagious pathogenic fungi that not only invade a wide range of crops but also induce severe allergic reactions in a part of the human population. In this study, two strains Alternaria longipes cx1 and Alternaria alternata cx2 were isolated from different brown spot lesions on infected tobacco leaves. Their complete genomes were sequenced, de novo ...

The allergens of Cladosporium herbarum and Alternaria alternata.